Clinical lycanthropy is an extreme form of a rare psychiatric disorder where the person believes they have transformed or are in the process of transforming into an animal, typically a wolf. This study had two main goals: examine the understanding of clinical lycanthropy in current psychology and psychiatry, and analyze if it is possible to look at Gregor Samsa from The Metamorphosis by Franz Kafka, as a meaningful example of acute psychological distress. This study utilized a quantitative description and primary data was derived from an anonymous 10-participant Google survey. The survey was 5 questions on the participants’ previous knowledge of clinical lycanthropy, their belief on if psychological disorders lead to the delusion of transformation, their ideas of the cause, their willingness to interpret psychological dispositions of fictional characters, and their thoughts on the public awareness and stigma. The data was reported as descriptive statistics and was compared to modern literature and theories. The data showed that there was little previous knowledge of the condition and half of the respondents did not recognize the term, and there was a strong support of psychological reasoning: 70% believed disorders can cause transformation beliefs, 70% accepted the psychological analysis of Gregor Samsa, and 80% believed that increased awareness would decrease stigma. The study found that clinical lycanthropy can be explained using modern psychopathology, and Kafka can be used to explain psychological disintegration, and that the awareness of clinical lycanthropy may decrease the stigma.